Call Us Today! 9837052040|[email protected]

Monthly Archives: April 2014

Incorrect biopsy results cloud Nymox Pharma prostate cancer study

(Reuters) – Nymox Pharmaceutical Corp said its experimental prostate cancer drug reduced the progression of cancer in patients, but it could not determine if the study succeeded in meeting pre-determined goals due to a high rate of incorrect biopsies.

In the mid-stage study, patients receiving a single injection of the drug, NX-1207, had less cancer progression in the treated area than in untreated patients.

The main goal of the trial was to show a significantly higher number of patients with undetectable prostate cancer after 45 days of treatment, compared to untreated patients.

However, the company was unable to assess the drug’s benefit because of a high percentage of false negative biopsies – a result suggesting there is no cancer present when it actually is – in the untreated patients’ group.

Nymox’s shares were down 3 percent at $4.98 in morning trading on the Nasdaq.

(Reporting by Esha Dey in Bangalore; Editing by Maju Samuel)

By |April 30th, 2014|blogs|0 Comments

Saudi camel tradition may hinder control of new disease

By Angus McDowall

RIYADH – The 40-odd men gathered in a sandy, dung-scattered auction pen at one of Saudi Arabia’s largest camel markets were fiercely dismissive of a link scientists have found between the animals and an often fatal virus in humans.

“It’s not true. It’s a lie. We live with camels, we drink their milk, we eat their meat. There’s no disease. We live and sleep and spend our whole lives with them and there’s nothing,” said Faraj al-Subai’i, a trader at the market.

The Middle East Respiratory Syndrome (MERS) virus has infected 345 people in the conservative Islamic kingdom since it was identified two years ago, causing fever, pneumonia and kidney failure in some, and killing around a third of sufferers.

Although many patients in a recent outbreak in Jeddah appear to have become infected through person-to-person transmission in hospitals, MERS has been found in bats and camels, and many experts say the latter form the most likely animal reservoir from which humans are becoming infected.

Camels occupy a special place in Saudi society, providing a link to an important but vanishing nomadic tradition and valued at prices that can climb to hundreds of thousands of dollars.

Last week the World Health Organization (WHO) advised people most at risk of severe disease to avoid contact with camels and take precautions when visiting places where the animals are present, and to avoid drinking raw milk.

Among the pungent animal pens in Riyadh’s camel market, stretching several miles along a highway out of the city, the traders, owners […]

By |April 30th, 2014|blogs|0 Comments

Amicus Therapeutics rare disease drug effective in trial

By Natalie Grover

(Reuters) – Amicus Therapeutics Inc said its experimental drug significantly reduced the abnormal accumulation of fat in body cells related to a rare genetic disorder that could lead to heart attack, stroke and kidney failure.

The company, whose shares rose as much as 36 percent, said it would file for U.S. marketing approval based on these results and those from an European trial, expected in the third quarter.

The late-stage trial evaluated the drug, migalastat, as a form of monotherapy for certain Fabry disease patients after 12 months of treatment.

The 24-month study began with a 6-month period where patients received either the drug or a placebo. All patients were then treated with migalastat for a 6-month follow-up period and a subsequent 12-month extension phase.

After the drug failed to show statistically significant reduction in kidney lipid levels at 6 months, Amicus said it would report 12-month efficacy and safety data to support its marketing application.

“It may be that (the drug) needs more time to work, as shown by today’s results,” Janney Montgomery Scott analyst Kimberly Lee said, adding that the European trial data would provide further evidence of whether the drug needed a longer duration to be effective.

Cowen & Co analyst Edward Nash said migalastat could satisfy the “significant need for an oral therapy for Fabry disease”.

Sanofi SA’s Fabrazyme, the first FDA-approved Fabry treatment, is administered intravenously.

Lee said she expected migalastat’s use as a monotherapy could represent a $250 million […]

By |April 29th, 2014|blogs|0 Comments

Nutrition Experts Offer Up Their Best Healthy Snacking Tips For Every Occasion

We asked our panel of nutrition experts when to snack, how to snack, where to snack and even why to snack in our most recent Twitter chat. Here are some of the highlights from our #snackchat:

By |April 29th, 2014|blogs|0 Comments

Daytime dozing may signal heart disease risk

By Kathryn Doyle

NEW YORK (Reuters Health) – Women who are often sleepy during the day tend to have underlying conditions that raise their risk of heart attack and stroke, according to a large new study.

Based on data for more than 84,000 U.S. women, researchers linked daytime sleepiness to a more than doubled cardiovascular risk, but they say sleep disorders and other illnesses are really to blame, making the drowsiness a symptom, not a cause.

“This is what we thought was going on,” lead author James E. Gangwisch told Reuters Health in an email. “We thought that it was most likely that the daytime sleepiness was associated with insufficient sleep, shift work, snoring, and sleep adequacy,” which are themselves associated with metabolic disorders like diabetes that are risk factors for stroke and heart attack, he said.

Gangwisch led the study at the College of Physicians and Surgeons at Columbia University in New York.

He and his coauthors analyzed data from 84,003 women in the Nurses Health Study II from 2001 to 2009. In the first year, the women answered a questionnaire that asked about sleep duration, disturbances, snoring and shift work.

One question asked how often a woman felt her daily activities were affected because she felt sleepy, and responses could range from “rarely” or “never” to “almost every day.”

The researchers kept track of other factors like shift work, aspirin use, diabetes and high blood pressure every two years until 2009.

By that time, five hundred of […]

By |April 29th, 2014|blogs|0 Comments